
Anti-Mouse F4/80 Antigen PE 抗小鼠F4/80抗原PE抗體
Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximay 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo
            
                     Host             Rat                              Isotype             IgG2a, kappa                              Reactivity             Mouse                              Conjugate             PE                              Laser             Blue Laser, Green Laser, Yellow-Green Laser                              Emit             575 nm                              Excite             488 - 561 nm                          Reported Applications             Flow Cytometric Analysis         
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